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ra0001p324 | (1) | WCRB2014

Effects of early exposure to bisphenol A, indole-3-carbinol, and/or genistein and the prostatic development in male rats offspring

Brandt Joyce Zalotti , Pinho Cristiane Figueiredo , Silveira Livia Teresa Ribeiro , Georgete Paulo Cesar , Bozano Jose Eduardo , Barbisan Luis Fernando , Scarano Wellerson Rodrigo

Bisphenol A (BPA) has been investigated for its potential carcinogenic activity for prostate. Studies have shown that indole-3-carbinol (I3C) and genistein (GEN) can activate antiproliferative and proapoptotic signaling pathways. The aim of this study was evaluate the influence of I3C (20 mg/kg) and GEN (5 mg/kg) on the development of prostate of offspring rats exposed during gestation and lactation to BPA (10 mg/kg). Pregnant female SpragueDawley rats were divided into ...

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Effects of early exposure to bisphenol A, indole-3-carbinol, and/or genistein and the prostatic development in male rats offspring

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